Granular bone grafting in the posterior lumbar fusion: a randomized controlled study

doi:10.3969/j.issn.2095-4344.2015.08.012

Abstract

Abstract:

BACKGROUND: Clinical usage of fusion cage for interbody fusion can reduce lumbar pain of patients with lumbar spinal stenosis, relieve nerve compression, and enhance the stability of the spine, but the limited long-term efficacy and high cost of treatment are two problems to be solved.

OBJECTIVE: To investigate the therapeutic effect of the granular bone grafting in the posterior lumbar fusion operation.

METHODS: Fifty-seven patients with L₃-S₁ lumbar spinal stenosis were randomly assigned into two groups: pedicle screw+granular bone to suppress interbody fusion in 27 patients (observation group) and interbody fusion cage for interbody fusion in 30 patients (control group). Visual analog scale score, Oswestry disability index, hospitalization expenses and the bed activity time were compared between the two groups before treatment, 1 month after treatment and at the last follow-up.

RESULTS AND CONCLUSION: There were no differences in the visual analog scale score and Oswestry disability index between the two groups before treatment, but at 1 month after treatment and at the last follow-up, these two scores were significantly lower in the observation group than the control group (P < 0.05). The hospitalization expenses were significantly lower in the observation group than the control group (P < 0.05), and no difference was found in term of postoperative bed activity time between the two groups. Granular bone grafting combined with pedicle screw fixation in the posterior lumbar fusion operation has reliable effects on reducing pain and promoting the functional recovery of the lumbar vertebra with low cost.

中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程

全文链接：

Key words: Bone Transplantation, Lumbar Vertebrae, Spinal Fusion

CLC Number:

R318

Wang Shi-hai, Liu Meng-jun, Wei Xin-wei, Wang Song, Chen Zhi-xin. Granular bone grafting in the posterior lumbar fusion: a randomized controlled study[J]. Chinese Journal of Tissue Engineering Research, 2015, 19(8): 1211-1215.

Figures/Tables 1

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